BRANMOOR
THURSDAY · 14 MAY 2026

FDA Recall D-1166-2022

Akcea Therapeutics, Inc. · Carlsbad, CA

Class I — life-threatening Terminated 316 days on record

Highest impact — Class I recall — FDA determination of strong likelihood of serious adverse health consequence or death.

Product

Tegsedi (inotersen) Injection 284 mg/1.5 mL, Rx Only, Sterile solution for Subcutaneous Use, 4 prefilled syringes, each containing 284 mg of inotersen, (equivalent to 300 mg inotersen sodium in 1.5 ml of solution), Distributed by Sobi, Inc. Inc Waltham MA 02451, NDC: 72126-007-01

Lot / code: Lots: 028C21AB, 028C21AC, Exp. 05/2025

Quantity: 450 cartons

Reason for recall

Superpotent: High Out of specification (OOS) test result for percent label claim (%LC).

Recall record

Recall number
D-1166-2022
Classification
Class I
Status
Terminated
Voluntary or mandated
Voluntary: Firm initiated
Firm notification
E-Mail
Distribution
KY, USA
Recall initiated
2022-05-23
Classified by FDA Center
2022-06-27
FDA published
2022-07-06
Terminated
2023-04-04
Recalling firm
Akcea Therapeutics, Inc.
Firm location
Carlsbad, CA

‹ All recalls